d50 troika! macguffins

1. single testicle of god
2. a pokédex
3. the tape from “escape from new york”
4. beautiful and sexy jewel thieves chase after the world’s rarest diamond so you’ll become really popular with sexy beautiful jewel thieves if you get it
5. baby with extremely huge head can be crawled into and if you do you get an automatically good idea
6. the six magic puppet strings to run the World Marrionette
7. angel wings + surgery (you can take people into or out of heaven)
8. the subtle knife
9. the smartest man on earth almost knows everything so you have to either prevent him or help him learn the last thing
10. workable portal to trove
11. working film projector / the know how
12. dictionary of all words, you can cross out words. also grammar nazis
13. other low hanging fruit??? someone’s trying to steal silk from the orient
14. the orient is trying to steal silk back heh heh
15. grocery store’s just trying to stay open versus an oppressive developer
16. sword in the stone but it’s still in the stage where everyone’s trying to politcally manuever around it
17. dick-stealing cat
18. rival adventure group doing an important thing and you’re continuously in the way by incriminating coincidence
19. death is trying to play chess with you
20. conflicting apocalyptic warnings and mutual demonization from two intelligent items
21. letting your players know the sun is going to burn out soon and then you’re going to end the campaign
22. aggressive suitors
23. fortune-teller warns of a dangerous sea voyage. quest-givers all try to get PCs to go on a voyage after this
24. bank holding all of their wealth fails
25. god begins sending you burning bushes, etc.
26. pursued by the apparently sentient idea of taxes
27. debt collectors making life difficult
28. divorce if at all applicable
29. kings hanging out with you
30. national feast in your honor goes hairy
31. inform a player that their coming-of-age ceremony is almost due
32. the draft
33. macular irregularity needs treatment or go blind
34. someone’s drone bombing your country
35. everyone seems to be adopting a prohibitive religious cult about an ear
36. prison 
37. jesus of nazareth doin stuff
38. bastardettes
39. seduced and organ stolen, keeps happening
40. grifters invade land
41. battle baby fights are becoming popular
42. roll again and work in trepanning
43. they look like they’re
1. meth addicts
2. cannibals
3. a secret psychic cult
4. but they’re actually:
1. evolved dinosaurs like in the super mario bros movie
2. rebellious women
3. communists
44. communism is being badly implemented
45. sherlock holmes trying to figure out that crime the pcs did
46. the connection between local street toughs and hidden goverment psychic kids program has grown too strong
47. the people have found a portal to (fake) heaven 
48. aliens land
49. incredibly violent ghost
50. serial killer sending in letters to the newspaper