"Destroyed."

Marc may or may not be telling the truth here; but his Jake Lockley persona has snuck around on him before.

Seemingly a million years ago, in our first strips with Satana, she had picked up the ability to grind up evil souls for magic power. Not being particularly motivated to do anything with said power, it's not come up a whole bunch. Would most of Spidey's villains even notice if they had lost their souls? The Goblin types probably not; one like Doc Ock, who has occasionally had outside interests besides being a dick, that would bother him.